Auristatin F是细胞毒性分子，微管蛋白修饰分子，强效抗**活性，MMAF的类似物以及在抗体药物偶连体开发中作为毒素分子。

 英文名称：Auristatin F

中文名称：奥瑞他汀 F

CAS：163768-50-1

抗体药物偶联物（Antibody-drug conjugate, ADC）是通过化学键将具有生物活性的细胞毒药物连接到单克隆抗体（mAb）上，单克隆抗体（mAb）作为载体将细胞毒药物靶向运输到目标细胞中发挥作用的一类药物。既具有细胞毒药物杀伤力强大的特点，又结合了重组单克隆抗体（mAb）高度的靶向性，稳定性和有利的药代动力学特征，主要表现为：治疗效力强；特异性高；免疫原性弱，不容易产生抗药性；血清中循环时间长（短于单抗）；对非靶点毒性弱等。

相关产品：

Dolastatin 10 110417-88-4  微管蛋白聚合抑制剂

Monomethyl Dolastatin 10 203849-91-6单甲基澳瑞他汀 D

Auristatin E 160800-57-7  一甲基澳瑞他汀

Monomethyl Auristatin E  474645-27-7微管相关抑制剂

Auristatin F 163768-50-1

Monomethyl Auristatin F 745017-94-1

HTI-286 228266-40-8

Tubulysin M 205304-86-5

Maytansinoid AP-3  66547-09-9

Maytansinol 57103-68-1

DM1 139504-50-0

DM4 799840-96-3

Boc-Val-Dil-Dap-OH

Boc-Val-Dil-Dap-Phe-OMe

Boc-Val-Dil-Dap-Doe

Boc-Val-Dil-Dap-Nrp

Boc-N-Me-Val-Val-Dil-Dap-OH

Tubulysin IM-1

Tubulysin IM-2

Tubulysin IM-3

Duocarmycin SA  152785-82-5

Duocarmycin TM

Duocarmycin MA

Duocarmycin DM

Nemorubicin 108852-90-0

PNU-159682 202350-68-3

Calicheamicin g1 108212-75-5

Acetyl-Calicheamicin g1 108212-76-6

a-Amanitin 23109-05-9

PBD-dimer 1222490-34-7

OSu-Glu-vc-PAB-MMAE

SMCC-DM1

SPDB-DM4

OSu-PEG4-vc-PAB-DMEA
Duocarmycin SA

Mylotarg-linker

OSu-Glu-vc-PAB-MMAD

Sulfo-SPDB-DM4

IMGN779-linker

OSu-PEG4-vc-PAB-DMEA

Duocarmycin TM

OSu-PEG4-vc-PAB-DMEA
Duocarmycin DM

MC-vc-PAB-MMAE

MC-MMAF

MC-DM1

MC-MMD-10

MA-PEG4-vc-PAB-DMEA-duocarmycin SA

MC-vc-PAB-C6-a-amanitin

MC-cleavable-linker-a-amanitin

MC-vc-PAB-DMEA-(PEG2)-duocarmycin SA

MC-vc-PAB-Tubulysin M

MC-va-PAB-MMAD

MA-PEG4-VC-PAB-DMAE-PNU159682

MA-PEG4-VA-PBD

MC-vc-PAB-MMAF

MC-vc-PAB-MMAD

MC-vc-PAB-Auristatin 0101

MA-PEG8-VA-PAB-SG3199

CL2A-SN 38

MC-GGFG-DX8951

MEDI4276_linker payload

MA-PEG4-vc-PAB-DMEA-duocarmycin TM

MC-vc-PAB-(PEG2)-duocarmycin TM

MA-PEG4-vc-PAB-DMEA-duocarmycin DM

MC-vc-PAB-(PEG2)-duocarmycin DM

DGN549

MPB-vc-PAB-MMAE

MPB-MMAF

DBCO-PEG4-vc-PAB-MMAE

DBCO-PEG4-MMAF

DBCO-PEG4-Ahx-DM1

DBCO-PEG4-vc-PAB-Duocarmycin SA

DBCO-PEG4-vc-PAB-(PEG2)-Duocarmycin SA

DBCO-PEG4-VA-PBD

DBCO-PEG4-vc-PAB-MMAF

DBCO-PEG4-vc-PAB-MMAD

DBCO-PEG4-vc-PAB-Duocarmycin TM

DBCO-PEG4-vc-PAB-(PEG2)-Duocarmycin TM

DBCO-PEG4-vc-PAB-Duocarmycin DM

DBCO-PEG4-vc-PAB-(PEG2)-Duocarmycin DM

DBCO-PEG4-VC-PAB-DMAE-PNU159682

DBCO-PEG4-DMAE-PNU159682

DBCO-PEG4-GGFG-DX8951

DBCO-PEG4-vc-PAB-Ahx-DM1

DBCO-PEG8-VA-PAB-SG3199

Gly3-vc-PAB-MMAE

Gly3-MMAF

Gly5-Ahx-DM1

PNU159682-EDA-Gly3

ADC pre-screening kit A

Protein A-DM1

Protein A-MMAE

Protein A-MMAF

Protein A-Duocarmycin

Protein A-Calicheamicin

Protein A-PBD

ADC pre-screening kit G

Protein G-DM1

Protein G-MMAE

Protein G-MMAF

Protein G-Duocarmycin

Protein G-Amanitin

Protein G-Amanitin

Rabbit Anti-vc-PAB-MMAE pAb

Mouse Anti-vc-PAB-MMAE mAb (B11F11)

Rabbit Anti-MMAF pAb

Mouse Anti-MMAF mAb (F3B11)

Mouse Anti-MMAE / F mAb (B12A2)

Mouse Anti-MMAE /F mAb (C12A1)

Rabbit Anti-DM1/4 pAb

Mouse Anti-DM1/4 mAb (F1D5)

Mouse Anti-DM1/4 mAb (G2F3)

Rabbit Anti-Calicheamicin pAb

Mouse Anti-Calicheamicin mAb (B1G9)&