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Hot APIs cancer
| Item No | Product Name | Product Description | Product Description | Inquiry |
|---|---|---|---|---|
| R-SX-720 | IDO inhibitor 1,CAS1204669-37-3 | Epacadostat, also known as INCB024360 or INCB24360, is an orally available hydroxyamidine and inhibitor of indoleamine 2,3-dioxygenase (IDO1), with potential immunomodulating and antineoplastic activities. IDO is an immunomodulatory enzyme produced by some alternatively activated macrophages and other immunoregulatory cells (also used as an immune subversion strategy by many tumors). Interferon-gamma has an antiproliferative effect on many tumor cells and inhibits intracellular pathogens such as | 查看详细 | |
| R-SX-721 | ACT-678689,CAS1783256-96-1 | ACT-678689,CAS1783256-96-1,西安瑞禧生物提供各种抑制剂材料。 | 查看详细 | |
| R-SX-722 | Avitinib (AC0010),CAS1557267-42-1 | Avitinib (AC0010)是不可逆的EGFR抑制剂，对于突变型EGFR具有选择性，对EGFR L858R/T790M双突变体的IC50为0.18 nM，是对野生型EGFR效力的近43倍（IC50=7.68 nM for WT EGFR）。Avitinib具有抗**活性和耐受性毒性。西安瑞禧生物提供各种抑制剂材料。 | 查看详细 | |
| R-SX-723 | LY2608204,CAS1234703-40-2 | LY2608204 activates glucokinase (GK) with EC50 of 42 nM. Phase 2.西安瑞禧生物提供各种抑制剂材料。 | 查看详细 | |
| R-SX-724 | Abemaciclib; LY2835219,CAS1231929-97-7 | Abemaciclib (LY2835219) 是具有选择性的 CDK4/6 抑制剂，能够抑制 CDK4/CDK6 的活性，IC50 分别为 2 nM 和 10 nM。 西安瑞禧生物提供各种抑制剂材料。 | 查看详细 | |
| R-SX-725 | 米卡芬净Micafungin;FK463,CAS235114-32-6 | Micafungin (Mycamine; FK463) 是抗真菌化合物，能抑制真菌细胞壁中的1,3-beta-D-葡聚糖合酶,西安瑞禧生物提供各种抑制剂材料。 | 查看详细 | |
| R-SX-726 | Eliglustat (Synonyms: Genz 99067),CAS491833-29-5 | Eliglustat是高效特异，有口服活性的葡糖脑苷脂合成酶抑制剂，IC50值为24 nM。 西安瑞禧生物提供各种抑制剂材料。 | 查看详细 | |
| R-SX-727 | UK-2A,CAS167173-85-5 | UK-2A,CAS167173-85-5,西安瑞禧生物提供各种抑制剂材料。 | 查看详细 | |
| R-SX-728 | AM580 (Synonyms: CD336; NSC608001; Ro 40-6055),CAS102121-60-8 | AM580是选择性的 RARα 激动剂，IC50 和 EC50 分别为8 nM，0.36 nM。西安瑞禧生物提供各种抑制剂材料。 | 查看详细 | |
| R-SX-729 | Brivaracetam;UCB 34714;UCB-34714;UCB34714; Briviact,CAS357336-20-0 | Brivaracetam has been tested in a comprehensive safety pharmacology, toxicology, developmental toxicology, and genotoxicity program. It is of low acute toxicity, target organ for toxic effects is the hepatobiliary tract. Carcinogenicity studies are ongoing. Human pharmacology studies have shown that brivaracetam has a half-life of 8 h and nearly complete bioavailability . CSD episodes were regularly elicited on slices upon delivery of calibrated KCl drops and were recorded via two micropipette e | 查看详细 | |
| R-SX-730 | Anamorelin ; RC-1291,CAS249921-19-5 | Anamorelin 是一种新型 ghrelin receptor 激动剂，FLIPR 检测中，EC50 为 0.74 nM。西安瑞禧生物提供各种抑制剂材料。 | 查看详细 | |
| R-SX-731 | Rolapitant;SCH619734,CAS552292-08-7 | Rolapitant (SCH619734)是高效选择性具有口服活性的 neurokinin NK1 受体抑制剂，Ki值为0.66 nM。西安瑞禧生物提供各种抑制剂材料。 | 查看详细 | |
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